I'm using a Nvidia card and I hear that causes problems, and I tried a couple of fixes from Lucasfiles, but neither one worked. Anyone have any help to give here?

For GeForce FX series and later cards, it is recommended that you disable "Application Control" on all settings and use the following settings:

Antialiasing=8x
Anisotropic Filtering=8x
Force mipmaps=Trilinear
Conformant texture clamp=On
Extension limit=Off

In the game, you get best results when the game's resolution setting matches the resolution of your Windows desktop.